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Efficacy of alogliptin, a dipeptidyl peptidase-4 inhibitor, on glucose parameters, the activity of the advanced glycation end product (AGE) - receptor for AGE (RAGE) axis and albuminuria in Japanese type 2 diabetes
The time line of experimental procedure was shown at Fig 1
The peptide influences vasomotor tone through the Src-caveolin-1-eNOS pathway, affecting both vasoconstriction and vasodilation depending on baseline vascular state
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