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Cardiovascular Health Visceral fat accumulation and insulin resistance increase cardiovascular risk

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No dosing or regimen recommendations are provided or implied for human or veterinary use

These studies span dose ranges that encompass probable human exposures

c-MET/HGF-targeted therapy such as the specific inhibitor SU11274 would be promising in at least a subset of SCLC patients with deregulated c-MET signalling through its overexpression or activating mutations