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Osteoporosis was experimentally induced using a high-fat diet with streptozotocin in two studies, ovariectomy in two studies, and dexamethasone administration in one study
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GLP-1 Medications and Eating Disorders - National Eating Disorders Association
While there is no established direct myotoxic or inflammatory effect on musculoskeletal tissues , any association with lower back pain is likely indirect rather than a direct pharmacological effect
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