In the context of chronic hyperlactatemia, lactate is viewed as both a byproduct and a contributor to metabolic dysfunction and systemic inflammation [144]
REDEFINE 2 (obesity with type 2 diabetes) A phase 3a, 68-week, double-blind, placebo-controlled trial across 12 countries (NCT05394519 [11] ) in 1,206 adults with BMI 27, HbA 1c 710%, and type 2 diabetes, randomised 3:1 to CagriSema 2.4/2.4 mg (n=904) or placebo (n=302)
So they may be best for older adults who dont enjoy cooking, those who dont have time to cook or those who are just looking for easy meal options
A malnourished mother on any weight loss medication, GLP-1 or otherwise, poses significant risk
Transitioning between these therapies requires careful monitoring of blood glucose , GI side effects, and treatment efficacy