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After 12 weeks treatment, the reductions in HbA1c from baseline were 0.96% with 1.8mg MAR709, 0.9% with 1mg tirzepatide and 1.7% with 5mg tirzepatide

After solubilization, the samples were analyzed for H and C content using dual window scintillation counting

The N-hydroxy analog of AMPH (i.e., N-OH AMPH), a metabolite of AMPH, also produces AMPH-like effects and is about twice as potent as AMPH (table 2)

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Acta Pharmacol Sin 35(2):257266 Zhang S, Rao S, Yang M, Ma C, Hong F, Yang S (2022) Role of mitochondrial pathways in cell apoptosis during he-patic ischemia/reperfusion injury