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The mean baseline BMI of participants was 31.8 kg/m2, and Mazdutide was administered at various doses: 3 mg, 4.5 mg, and 6 mg
DIO mice were randomized to treatment according to body weight (n = 15 per group) and dosed subcutaneously (5 ml/kg) for a total of 28 days with vehicle (QD), liraglutide (0.2 mg/kg, BID) or GUB09-145 (0.04 mg/kg, BID)
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Therefore, Tirzepatide creates a greater physiological effect than traditional GLP-1 receptor agonists like Semaglutide
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