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For patients who've failed semaglutide (insufficient weight loss, plateau at target doses, or intolerance), tirzepatide is increasingly the second-line option

In a clinical trial of semaglutide injection for weight loss (Wegovy) in patients with T2DM and a BMI of 27 kg/m2 or more, hypoglycemia (defined as a plasma glucose less than 54 mg/dL) was reported in 6.2% of semaglutide-treated patients versus 2.5% of placebo-treated patients

While bowel habits are highly individual, general indicators of constipation include: Infrequent Bowel Movements: Typically, fewer than three bowel movements per week

On just the Hims & Hers platform alone, nearly 80,000 individuals have shared they cannot access branded GLP-1 medications