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Then, cells were switched to medium 1 for 5 additional days after which they exhibited a fully differentiated phenotype and were used for experiments
Effects of liraglutide combined with short-term continuous subcutaneous insulin infusion on glycemic control and beta cell function in patients with newly diagnosed type 2 diabetes mellitus: a pilot study
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In addition, lactate-induced lactylation stabilizes HIF-1 under normoxic conditions, facilitating its transcriptional activity on angiogenic targets (KlAA1199 axis) in prostate cancer cells and contributing to vascular remodeling [93]
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