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Although results vary among patients, most individuals can expect to see these enhancements last for half a year

Side effects and how to minimize them DSIP appears to be well-tolerated in research settings, with no major toxicity identified even at high doses

IntMed J 2007]

This work is suspected of not respecting ethical and scientific standards and is, for some, the subject of ongoing legal proceedings. After years of criticism, including a 2023 letter raising serious concerns about methodological flaws in the study and an editorial conflict of interest (one of the co-authors was also editor-in-chief of the journal), the journal finally issued a lengthy retraction notice

The mechanism for this has been observed in rat brain mitochondria