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Hardeland, R
Hill, A.K
Many classical ferroptosis inducers, such as erastin and RAS-selective lethal 3, can target the xCT/GPX4 axis, and these inducers can trigger ferroptosis in cancer cells, suggesting they hold promise in the treatment of cancer [40, 42]
To advance personalized treatment strategies, it is critical to improve current understanding of the overlapping pathophysiology as well as the heterogeneity of obesity and diabetes, including their multi-hormonal dysregulation and inter-individual differences [24, 25]
Lee et al., 2022), MK-886 (Shi et al., 2023), BWA4C (Franchi-Miller and Saffar, 1995), PD146176 (Walters et al., 2018) and others
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