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A potent CysLT1 receptor antagonist, montelukast inhibits the activation of the NF-B pathway and secretion of IL-6 and IL-8 in FLS (165), next to reducing the disease incidence and its activity (166)
But the potential for the very high efficacy of an injectable to be achievable via a pill represents an important path going forwardit could help markedly reduce the cost and uptake
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