semaglutide ckd approval Poll: Do you think we'll see new FDA for semaglutide, specifically or Heart Failure and/or CKD, in 2025? 💊 This post highlights primary takeaways from 2 major trials from the past ~ Semaglutide could be 'practice changing'

Scheiblich H, Eikens F, Wischhof L, Opitz S, Jngling K, Cserp C, Schmidt SV, Lambertz J, et al

Access to manufacturer savings and copay facilitation options further amplify affordability

MC4R is predominantly localized within the hypothalamic regions of the central nervous system and is speculated to modulate energy homeostasis and neurobehavioral functions

One possible mechanism involves abnormal cathepsin maturation, which alters its interaction and localization within lysosomes during pancreatitis, enabling cathepsins to hydrolyze LAMP proteins

Clinical trials have demonstrated the efficacy of semaglutide in promoting significant weight loss