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doi: 10.1038/s41467-021-27766-8 62

Rarely, patients may experience hypersensitivity reactions to cobalt or vitamin B12, including rash, itching, acneiform eruptions, or in exceptional cases, anaphylaxis

Vitamin B12 deficiency is more prevalent than many people realise: Around 6% of the UK population has B12 deficiency This rises to approximately 20% in those over 60 An estimated 1 in 10 people in the UK may have inadequate B12 levels 6% of men and 10% of women aged 19-64 have low serum B12 concentrations Among women of reproductive age (19-49), 11% have low B12 Interestingly, research suggests that deficiency is often due to absorption problems rather than dietary intake

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