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Meanwhile, a DNG s construct with 8 mutations (S54N, G226A, E268A, N271K, K274D, R280K, T284D and I285T) was used to help stabilize the peptide 20GIPRG s complex 38,51
Patients transitioning from liraglutide to tirzepatide are therefore moving to a drug that has demonstrated roughly 2.5 times greater mean weight loss in separate trials
Abstract presented at: Heart Rhythm 2025
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