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Vit B12 status is also considered as a modulating factor of the phenotypic expression of PD as recent data have intriguingly suggested a potential role of Vit B12 deficiency in motor progression in PD assessed using the Unified Parkinsons Disease Rating Scale (UPDRS) and the ambulatory capacity score and the worsening of cognitive dysfunction evaluated via the mini-mental status examination (MMSE) (Christine et al

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Visible changes may be caused by diluent incompatibility, pH shift, ionic effects, concentration effects, or peptide-specific solubility behaviour