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By the 12 to 16-week mark, many individuals experience the full effects, which can include a significant reduction in body weight, often around 5% to 10% or more of their starting weight
Postmenopausal women who carried the C677T variant had a 2 to 3-fold increased risk of depression.[ref] Women with two copies of the A1298C variant were at twice the risk of major depressive disorder (MDD)
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In fact, some analyses suggest lower recurrence rates or improved outcomes in those who develop pancreatitis while on therapy
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