Rewriting the will: Autonomy and pharmacological desire modification in semaglutide use [PMID: 41033788] Laboratory literature summary: Rewriting the will: Autonomy and pharmacological desire modification in semaglutide use
Hypothyroid patients losing 5-10% of body weight sometimes experience mild symptoms of overtreatment (mild tremor, increased heart rate, anxiety) even though their thyroid medication dose hasn't changed
Wang B, Hu Z, Cui L, Zhao M, Su Z, Jiang Y, et al
and actually SARS-CoV-2 causing COVID-19, all are characterized by persistent inflammation, continuous production of reactive oxygen/nitrogen species and oxidative stress that predominate over the antioxidant defenses (GSH and free radical scavenger enzymes) resulting in cell/tissue/organ aging associated with early (premature) chronic inflammation/inflammaging. We propose that, although inflammaging was introduced for the aging process (276289), it could also apply to early (premature) tissue and organ aging associated with cell and tissue damage caused by excessive oxidative stress and lack of adequate antioxidant defenses, especially low GSH levels, in younger individuals
At this time, GLP-1/GIP medications should not be represented as disease-modifying therapy for autoimmune disorders