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The SGLT2 Comparison Was More Complicated The comparison against SGLT2 inhibitors is especially valuable because it places GLP-1 receptor agonists against another modern metabolic drug class rather than older diabetic therapies

Retrieved from Goyal, A., Daneshpajouhnejad, P., Hashmi, M

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Figure 6 shows that the hydrophobic sidechains of Ile1 and Ile 3 of Diprotin A are in close proximity, and this hydrophobic interaction may stabilize the peptide in an conformation that is not suitable for reaction progression