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In addition to aesthetic treatments consider: Optimise protein intake (0.8-1.2 g/kg of body weight) to preserve muscle mass Use medical grade skincare with ingredients such as retinoids, peptides and vitamin C Stay hydrated to maintain skin elasticity While GLP-1 medications offer transformative weight loss and health benefits, they can lead to unintended facial changes

GLP-1 injections, such as Ozempic (semaglutide) and Wegovy (semaglutide), are commonly prescribed for type 2 diabetes and weight loss

Glycine, an important one-carbon source, is the third amino acid added to -glutamylcysteine, the condensation product of glutamate and cysteine, to form glutathione (Figure 1)

It mimics ghrelin and binds to the ghrelin receptor (GHSR) in the brain, selectively stimulating GH release from the pituitary gland, which increases plasma GH levels

These findings have provided valuable insights into the management of T2D and informed clinical practice guidelines and regulatory decisions.GLP-1 receptor agonists have emerged as an important therapeutic option for individuals with T2D, particularly those at high risk of CVD