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M., Makeyev, E

A case report published in Cureus described a biphasic anaphylactic reaction occurring 20 minutes after tirzepatide injection, with diffuse urticaria, throat swelling, shortness of breath, and wheezing

Duan H, Jing L, Xiang J, Ju C, Wu Z, Liu J, Ma X, Chen X, Liu Z, Feng J, Yan X (2022) CD146 associates with Gp130 to control a macrophage pro-inflammatory program that regulates the metabolic response to obesity

Criteria include: Eating an abnormally large amount of food Experiencing loss of control Eating far more rapidly than normal Eating until uncomfortably full Consuming large amounts of food when not physically hungry Eating alone out of embarrassment for the quantity Self-loathing, depression, or guilt after overeating Doctors dont consider purging food, vomiting, taking laxatives, or overexercising to be diagnostic criteria for binge-eating disorder, and the behaviors above must occur at least once a week

Especially, we thank Atsuhito Tone, Hideo Machimura, Hidetoshi Shimura, Hiroshi Takeda, Hisashi Yokomizo, Kei Takeshita, Keiichi Chin, Masaaki Miyauchi, Masuo Saburi, Miwa Ohta, Miwako Yomota, Moritsugu Kimura, Nobuo Hatori, Shinichi Nakajima, Shun Ito, Takashi Murata, Takayuki Furuki, Takuya Hashimoto, Tomoya Umezono, Yuki Senda, and Yuichi Takashi, who contributed the RECAP study