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The findings of this study indicate that DHB delivers the beneficial metabolic effects of berberine in a more absorbable form and at a lower dose.*5 A small, randomized, double-blind, crossover pilot study (N = 5) investigated the absorption kinetics and compared the dosing of berberine and DHB required to achieve peak plasma concentrations

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For COPD, higher doses such as 500 mcg to 1000 mcg daily are common, often in combination inhalers