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This usually happens after a steroid cycle because anabolic steroids suppress the bodys natural testosterone levels and elevate estrogen levels, which can cause gynecomastia, water retention, and mood swings

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[7] [9] Usage depends on eGFR thresholds, and patients should receive sick-day guidance (temporarily stopping during acute illness) Thiazolidinediones (e.g., pioglitazone): May improve insulin sensitivity but carry risks of weight gain, fluid retention, and fractures [11] [17] Sulfonylureas (e.g., gliclazide): Effective but associated with hypoglycaemia and weight gain Basal insulin : For patients with significant hyperglycaemia, especially if symptomatic or with very high HbA1c (75 mmol/mol or 9%), insulin therapy may be necessary DPP-4 inhibitors (e.g., sitagliptin) are an alternative class of medication when GLP-1 receptor agonists are unsuitable