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These gastrointestinal side effects are the most common with semaglutide and are usually manageable with lifestyle adjustments and time

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Sedeek M, Nasrallah R, Touyz RM, Hbert RL

The most recent and methodologically rigorous of them, restricted to four placebo-controlled trials in 667 patients, found no significant difference from placebo on MDS-UPDRS Part III in either the on- or off-medication state [7]

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