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2014;XIV:416

Single and multiple dose pharmacokinetics of tesamorelin have been characterized in healthy subjects and HIV-infected patients without lipodystrophy following 2 mg subcutaneous administration

In the body, IGF-1 plays a role in: Cellular repair Muscle tissue regeneration Collagen synthesis Metabolic signaling Because of its prolonged activity, IGF-1 LR3 dosing requires careful clinical oversight

(33480193) Morbid obesity : Use of an adjusted body weight might be reasonable to avoid excessive doses