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Individual non-responder: Small percentage of individuals don't respond to specific interventions regardless of quality or dosing
In particular, we focused on the p21 N-terminal cyclin-CDK binding domain, required for inhibition of G1/S cell cycle progression, and the C-terminal PCNA binding domain involved in suppressing DNA synthesis (Chen et al, 1995) (Fig 2D)
San Diego 's keel was laid down on 23 May 2007, at Northrop Grumman's Ingalls shipyard in Pascagoula, Mississippi
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iii) BSO also enhanced the antiproliferative effect of gemcitabine in BTC cells
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