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In that treatment group, the average weight loss was 10.2% on a once-weekly dose of 2.4 mg

In comparison, vitamin B6 has a prominent role in hormone regulation, neurotransmitter synthesis, and protein synthesis

Physician-monitored for dosing and safety

Options include: Walking, starting with whatever distance feels comfortable Swimming or water-based exercise, where buoyancy reduces joint loading Cycling (stationary or outdoor), which keeps joints moving without heavy impact Gentle yoga or tai chi for flexibility and balance A systematic review of aquatic exercise for OA found it was effective for reducing pain, improving joint function, and improving quality of life