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NICE Guideline NG193 recommends exercise therapy, psychological interventions such as CBT, patient education, and consideration of acupuncture as first-line treatments

The unknown rate constants for R 1 , R 2 , R 3 , R 4 and R 5 for the respective models were fitted using the LSQNONLIN function in MATLAB, a non-linear least squares solver

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R This is why NAC (N-acetylcysteine) is so relevant to detoxification: it serves as a precursor to both glutathione synthesis and as the end-product template for mercapturic acid excretion