Always follow your doctors instructions and never guess the dose
Rather than sedating, it appears to normalize disrupted sleep architecture in animal and small human studies
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A 0.25 mg starting dose requires 0.1 mL, which is 10 units on a U-100 insulin syringe
N Engl J Med 362(9):774777 Mavrakanas TA, Tsoukas MA, Brophy JM, Sharma A, Gariani K (2023) SGLT-2 inhibitors improve cardiovascular and renal outcomes in patients with CKD: a systematic review and meta-analysis