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A haemagglutinin (HA) signal peptide was added to the N-terminus of GLP-2R to increase the expression level
Gallbladder Disease: Increased risk of gallstones, especially in individuals with existing gallbladder problems
Unlike traditional diabetes drugs, GLP-1 therapies are often intended for long-term or even lifelong use
Recovery is assessed based on clinical stability, improving hepatic biomarkers (AST, ALT, INR, bilirubin), and normalization of metabolic parameters
It is contraindicated for anyone with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, due to the thyroid-related findings observed in animal studies
