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Ruiz et al., 2015), 12 weeks (Forti et al., 2014), and as long as 9 months in individuals with type 2 diabetes (Swift et al., 2012) have not been shown to change basal serum BDNF
doi: 10.1002/dmrr.3042 24 ChoiY.BoseS.SeoJ.ShinJ
Initial investigations into the cardiovascular safety effects of glucose-lowering medications in patients with T2D revealed an unexpected reduction in CV complications and mortality with the use glucagon-like peptide 1 receptor agonists (GLP1-RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2is)
The combination may result in more severe or prolonged gastrointestinal symptoms, potentially leading to dehydration, electrolyte imbalances, or nutritional deficiencies if food intake becomes severely restricted
Huang F, Shen X, Zhang Y, Vuong AM, Yang S
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