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To further explore the TYR degradation performance of VH032-Azi3 + Alk-TIn + SA treatment group, we performed the dose- and time-dependent experiments, in which higher doses and longer treatment time resulted in better degradation efficiency (Supplementary Figs

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While incretin signaling improves glycemic control and inflammatory tone, sustained hypophagia shifts the locus of metabolic regulation toward substrate availability and metabolic throughput

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