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The primary evidence comes from the 2017 Cell paper using aged and chemotherapy-treated mice, and subsequent mechanistic studies

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Um deles, conduzido aqui no Brasil e publicado nos Arquivos Brasileiros de Endocrinologia e Metabologia, avaliou por 30 dias os efeitos do consumo da substncia e no constatou nenhuma mudana na composio corporal ou na reduo de peso dos participantes

Supplementary Figure 5 Enrichment analysis of upregulated and downregulated pathways