96 participants were randomly assigned to groups of 6 multiple-ascending doses of once-weekly subcutaneous cagrilintide (final doses of 0.16, 0.30, 0.60, 1.2, 2.4, and 4.5 mg) in combination with once-weekly subcutaneous semaglutide 2.4 mg or semaglutide 2.4 mg with placebo for 20 weeks
Finally, as a newer provider, long-term outcomes and large review datasets are still sparse
This means you draw your dose using a syringe, which requires understanding unit-to-milligram conversions
Patients should not exceed 8 mg per day without medical supervision and should avoid loperamide if they have fever or bloody stools
It's worth noting that obesity itself is associated with higher rates of sexual dysfunction, and many patients report improvements in sexual health following successful weight loss, once they've adjusted to their new weight and the medication has stabilised