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Figure 13 illustrates the effects of prenatal exposure to VPA, showing that HDAC inhibition may exacerbate oxidative stress by dysregulating the expression of genes involved in the antioxidant response, thereby promoting redox imbalance through increased ROS production and impaired antioxidant defenses (Gottlicher 2001

OKusky J, Colonnier M (1982) Postnatal changes in the number of neurons and synapses in the visual cortex (area 17) of the macaque monkey: a stereological analysis in normal and monocularly deprived animals

found that GSTM2 expression was much higher in ovarian teratoma mesenchymal stem cell-like cells than in normal cells and that p38 was highly inhibited in the teratomas 43

One vial lasts ~29 days

Because BPC-157 lacks robust human safety data across the proposed routes of administration, the FDA states it does not have enough information to know whether compounded BPC-157 would cause harm in humans