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Grauer GF, Greco DS, Getzy DM, et al
Neuroimage 197 , 502511 (2019)
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Patients might be women in their 30s with an autoimmune disease like lupus or people of any age exposed to such toxins as methamphetamines or, in the past, the fen-phen appetite suppressant drug of the 1990s, later withdrawn after being linked to heart disease
This discrepancy between formal trial data and patient-reported experiences may reflect several factors: cold sensitivity might not have been specifically monitored in trials, it may be attributed to weight loss rather than the medication, or it might affect only a subset of patients
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