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The company, which will present full data from the study later this year, said it would file for an expanded approval of Ozempic based on the data in both the U.S

This is not a direct drug-to-drug chemical interaction, but rather an additive effect on a common side effect pathway

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Although the percentage of patients in the placebo group who had an improvement in fibrosis stage in this trial was similar to the percentage of patients in the placebo group of the PIVENS (Pioglitazone versus Vitamin E versus Placebo for the Treatment of Nondiabetic Patients with Nonalcoholic Steatohepatitis) trial who had an improvement in fibrosis stage (31%), 24 it was greater than that reported in several other trials

Neurology 48: A 150