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We identified downregulation of mitochondrial programs in multiple non-proximal tubular cell populations compared with their counterparts in healthy kidneys

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The highest intracellular concentration of GSH was 186.77 mg/L produced by strain W303-1b/F, and most of the synthesized GSH could be attributed to the function of the introduced GshF as strain W303-1b/gsh1/F yielded a similar amount (about 90 %) GSH to W303-1b/F

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