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Although we could not exclude the influence of different isolation procedures for each organ, along with the glutathione accumulation within TLS, these findings suggest that TLS in the kidney represent a unique microenvironment characterized by a dynamic equilibrium between oxidative stress and glutathione accumulation, which may play a pivotal role in regulating the formation of TLS and its function
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In addition, the maximum levels of iNOS mRNA also found at 60 h were significantly lower than those in the WT livers, and the protein was detected later at 6072 h post-PH