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The FDA has issued warning letters to compounding pharmacies that produced GHRP-6 formulations for human use, stating that such products are unapproved new drugs and do not meet the conditions for compounding exemptions under Section 503A of the Federal Food, Drug, and Cosmetic Act

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Dihexa contains aromatic moieties that are vulnerable to photo-oxidative degradation when exposed to direct sunlight or intense ultraviolet (UV) laboratory lighting

Other GLP-1/GIP/GCG Triple Agonists in Development Besides retatrutide, several GLP-1/GIP/GCG triple agonists are in early-stage clinical trials (Table 3), though the WL efficacy associated with these medications remains unknown