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Cells were washed to remove viral particles and transduced cells were selected in the presence of 1 g/ml puromycin (Sigma-Aldrich, P8833) for at least 96 h

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Furthermore, the redox activity of PDI, but not its chaperone function, rescued motor dysfunction and axonopathy in zebrafish models of ALS expressing mutant SOD1, together implying that PDI has an important role both in vitro and in vivo (Parakh et al., 2020)

Patients often experience: Nausea Vomiting Diarrhea Constipation These symptoms can be particularly bothersome and may affect a patients willingness to continue the medication

When sleep is disrupted, many people start looking for deeper answers than over-the-counter sleep aids or short-term sedatives