The data on rhIGF-1 support the mechanistic rationale that an IGF-1 analog like LR3 (which has extended half-life and greater receptor availability in research settings) could enhance protein synthesis, stimulate cellular proliferation pathways and promote more efficient nutrient partitioning, though direct clinical trials of IGF-1 LR3 itself in humans are lacking
Integrative medicine (Encinitas, Calif.) , 13 (1), 812 Zakeri, N., kelishadi, M
Erythrocyte metabolism
Study Design: during the 3-week study, 16 participants consumed 150 grams of goats milk fermented with Lactobacillus fermentum ME-3 (test group) while 5 participants ingested 150 g fresh goats milk without probiotics (control group)
This dialysis bag was then immersed in either 200 mL of phosphate-buffered saline (PBS) or a 200 mL aqueous solution of hydrogen peroxide (H 2 O 2 ) at a concentration of 10 mM, all while being maintained in a shaking culture incubator at 37 C