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Diet, supplements (e.g., niacin, NR), and exercise help, but may not suffice post-40 due to inefficiency and depletion.[18][19] Oral precursors like NMN increase NAD+ but bioavailability varies

Many people have genetic variations that make this conversion inefficient, which is why Methyl B12 is often more effective

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Research focus: metabolic health, obesity models, and cellular energy dynamics