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If the dose is correct, ensure your tirzepatide has been stored properly
One hypothesis is that chronic GIP receptor agonism desensitizes the GIP receptor, creating an antagonism, which ultimately leads to weight loss
Some users find that warm water is tolerated better than cold, possibly because warmth relaxes gastric smooth muscle
These reactions are usually mild and go away on their own
Shi N, He J, Guo Q, Liu T, Han J
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