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Holding that discipline is what ensures first do no harm remains central, particularly in health-conscious individuals where potential benefit is uncertain and avoidable risk matters more

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In animal models the parent compound is described as relatively short-lived in plasma but with effects persisting longer than the systemic exposure window a profile the Zagreb group attributes to its stability in the gastrointestinal lumen and to downstream signaling cascades (Sikiric et al., 2018)