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The largest trial involving DSIP to date, which included a total of 107 volunteers, reported that the peptide was generally well-tolerated with mostly minor side effects, which included [8]: Low blood pressure Increased sweating Headache Nausea Vertigo Considering that the drop in blood pressure was reported as moderate to severe in some patients, researchers should consider hypotension as a potentially exclusionary criterion for DSIP research

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However, if a specialized laboratory test is used, stable metabolites of the peptide can typically be detected for roughly 24 to 48 hours after administration, with some studies suggesting trace detection up to 4 days later

E., Wagner, T

Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats After Focal Stroke