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The Cochrane Collaboration, Chichester, UK: John Wiley & Sons

There is one open-label intravenous safety pilot in two healthy adults, who received single doses of 10 mg and 20 mg with no comparator, no blinding, and short-term observation limited to vital signs, self reported symptoms and labs across two days [4]

For medical use, see Cyanocobalamin injection for adverse effects and precautions

It is found almost exclusively in animal-derived foods and requires intrinsic factor for absorption

Timelines Are Measured in Weeks to Months Patients expecting dramatic results within days are likely to be disappointed