Abstract Epicardial adipose tissue (EAT), a metabolically active visceral fat depot anatomically contiguous with the myocardium, has emerged as a critical mediator and promising metabolic therapeutic target in atrial fibrillation (AF), particularly in the context of obesity and diabetes mellitus
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Subsequently, 10 L of 100 M ActivX Desthiobiotin-FP Serine Hydrolase Probe (Thermo-Fisher Scientific) was added, resulting in final concentrations of 100 M PMO and 2 M FP probe
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