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The coenzymes, NAD and NADP) facilitate essential oxidation-reduction reactions
Gradual increase: Doses are slowly increased every 4 weeks or as tolerated
doi: 10.1038/nature22394 44 FinanBMaTOttawayNMllerTDHabeggerKMHeppnerKMet al
755 Mechanistically, SSAT1 overexpression increases ALOX15 expression and decreases the expression levels of GPX4 and SLC7A11 in primary cortical neurons, suggesting that SSAT1/ALOX15 axis activation may aggravate brain I/R injury by triggering ferroptosis in neurons
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