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Fludra M, Kobosko J, Gos E, Paluchowska J, Skarzynski H
it is not FDA-approved and is not therapeutically equivalent to Zepbound or Mounjaro, which come in fixed-dose pens
J., & Hall, M
33 GLP-1 also reduces hepatic production of glucose by reducing the expression of key metabolic regulators of glycogenolysis
As noted, endogenous GLP-1 has a very short half-life of 12 min because it is rapidly degraded by the enzyme DPP-4, which results in low systemic levels
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