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This method quickly fills up B12 stores
PMID 6420106
A practitioner asking should I offer MIC? in 2026 is implicitly asking why would I, when I can prescribe a GLP-1? The honest answers are narrower than the marketing, but they are real: Patients who cannot or will not take a GLP-1
in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )
Comparing your results to others is generally unhelpful
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